After setting your destination, set the tabindex to the GO button.
When you finally tell waze to navigate, it has this additional pop up. The popup does not have the hightlight/active button on the go button (to start navigating), but on the favorite (star) button. This is unintuitive. I had to use the dial while driving, hopefully find the GO button, and then press enter to start the navigation instead of just pressing enter in one go.